CD3 epsilon / APC-Cy5.5 / 500A2

Product Details
Description Monoclonal
Conjugate APC-Cy5.5
Clone 500A2
Target Species Mouse
Applications FC
Supplier Abcam
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About CD3 epsilon
The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]
About APC-Cy5.5
APC-Cy5.5 has an excitation peak at 651 nm and 695 nm and is useful in flow cytometry. However, alternatives like APC-Alexa 680 and APC-R700 have proved better in many stability tests.
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