CHREBP / DyLight 550 / Polyclonal

Product Details
Description CHREBP Polyclonal Antibody, DyLight 550 conjugate. ChREBP is a transcription factor involved in activating genes that encode enzymes of fatty acid biosynthesis in liver and adipose. This protein may have relevance to lipid metabolism, obesity, and type II diabetes.ChIP 1:10-1:500, IF 1:100-1:500, IHC (P) 1:100, WB 1:1000, ICC 1:100-1:500
Conjugate DyLight 550
Clone Polyclonal
Target Species Human, Mouse, Rat
Applications IF, ICC, WB, ChIP
Supplier Thermo Fisher Scientific
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About CHREBP
This gene encodes a basic helix-loop-helix leucine zipper transcription factor of the Myc/Max/Mad superfamily. This protein forms a heterodimeric complex and binds and activates, in a glucose-dependent manner, carbohydrate response element (ChoRE) motifs in the promoters of triglyceride synthesis genes. The gene is deleted in Williams-Beuren syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at chromosome 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
About DyLight 550
DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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