IRE1 alpha / DyLight 550 / Polyclonal

Product Details
Description IRE1 alpha Polyclonal Antibody, DyLight 550 conjugate. IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator. It is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities. Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER.WB 1:1000-1:2000
Conjugate DyLight 550
Clone Polyclonal
Target Species Human, Mouse, Rat
Applications WB
Supplier Thermo Fisher Scientific
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About DyLight 550
DyLight™ 550 has an excitation peak at 562 nm and an emission peak at 576 nm and is spectrally similar to Alexa Fluor™ 546, Alexa Fluor™ 555, Cy3 and TRITC. DyLight™ 550 is most commonly used in flow cytometery and fluorescence microscopy applications.
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121 IRE1 alpha antibodies from over 6 suppliers available with over 33 conjugates.

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