IRE1 alpha / DyLight 488 / Polyclonal

Product Details
Description IRE1 alpha Polyclonal Antibody, DyLight 488 conjugate. IRE1 acts as the sensor of unfolded proteins in the ER that initiates transmittance of the unfolded protein signal from the ER to the nucleus by splicing XBP1 mRNA converting it into a potent unfolded-protein response transcriptional activator. It is a transmembrane protein that has both serine-threonine kinase and endoribonuclease activities. Null mutants are viable, but IRE1 is essential for viability under stress conditions that cause unfolded proteins to accumulate in the ER.WB 1:1000-1:2000
Conjugate DyLight 488
Clone Polyclonal
Target Species Human, Mouse, Rat
Applications WB
Supplier Thermo Fisher Scientific
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About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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121 IRE1 alpha antibodies from over 6 suppliers available with over 33 conjugates.

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