PHF-tau (pS202/pT205) / Biotin / AT-8

Product Details

Description	Phospho-PHF-tau pSer202+Thr205 Monoclonal Antibody, Biotin conjugate (AT8). Paired helical filament (PHF) is a major component of the neurofibrillary tangles involved in the pathology of Alzheimer's disease. PHFs are composed of the microtubule-associated protein tau in a hyper-phosphorylated state (ref1). Tau protein is produced by a single gene expressed predominantly in neurons. The Tau gene undergoes complex alternative splicing, yielding six different isoforms of tau in the adult brain. Following translation, the tau protein can be further modified by phosphorylation at several different sitesIF Assay Dependent, WB Assay Dependent, IHC (P) Assay Dependent, ICC Assay Dependent, ELISA Assay Dependent
Conjugate	Biotin
Clone	AT-8
Target Species	Human
Applications	ELISA, IF, ICC, WB, IHC
Supplier	Thermo Fisher Scientific
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