CD11c / PE-Texas Red / N418
Product Details
Description | CD11c Monoclonal Antibody (N418), PE-Texas Red | |
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Conjugate | PE-Texas Red | |
Clone | N418 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Thermo Fisher Scientific | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD11c
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]
About PE-Texas Red
PE-Texas Red is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Texas Ted. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Texas Red. PE-Texas Ted has an excitation peak at 565 nm and an emission peak at 615 nm. It is spectrally comparable to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594.
PE-Texas Red is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Texas Ted. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Texas Red. PE-Texas Ted has an excitation peak at 565 nm and an emission peak at 615 nm. It is spectrally comparable to PE-eFluor™ 610, PE-Dazzle 594 and PE-CF®594.
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Validation References
PMID 10427977 | |
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PMID 18391003 | |
PMID 21214540 | |
PMID 24098126 | |
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Reviews & Ratings
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