CDC47 / Biotin / 47DC141 or DCS-141

Product Details
Description CDC47 Monoclonal Antibody, Biotin conjugate (47DC141 or DCS-141). hCDC47 is a human member of the MCM family, which allows DNA to replicate once per cell cycle. In quiescent cells, human MCM7 (hMCM7) mRNA is almost undetectable. Stimulation of cells to enter the cell cycle results in induction of hMCM7 expression. The hCDC47 protein expression and localization is found in nuclei of the proliferative components of normal lymph nodes, bone marrow, epidermis and mucosa. Malignant tumors from several organs contained more nuclear hCDC47-positive cells than their normal counterparts. These results indicate that hCDC47 may play a role in normal and neoplastic cell growth in vivo.IF Assay Dependent, IHC (P) 0.5-1.0 µg/ml, IP 2 µg/ml, WB 1-2 µg/ml
Conjugate Biotin
Clone 47DC141 or DCS-141
Target Species Canine, Human, Mouse, Rat
Applications IF, WB, IHC
Supplier Thermo Fisher Scientific
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