Neuroserpin / Biotin / Polyclonal
Product Details
| Description | To detect Human Neuroserpin by Western Blot analysis this antibody can be used at a concentration of 0.1 - 0.2 mg/ml. When used in conjunction with compatible development reagents the detection limit for recombinant Human Neuroserpin is 1.5 – 3.0 ng/lane, under either reducing or non-reducing conditions. To detect Human Neuroserpin by sandwich ELISA (using 100 ml/well) a concentration of 0.25 – 1.0 μg/ml of this antibody is required. This biotinylated polyclonal antibody, in conjunction with PeproTech's Polyclonal Anti- Human Neuroserpin (500-P271) as a capture antibody, allows the detection of at least 0.2 – 0.4 ng/well of recombinant Human Neuroserpin. To detect Human Neuroserpin by direct ELISA (using 100 ml/well) a concentration of approximately 1.0 μg/ml of this antibody is required. This biotinylated polyclonal antibody allows the detection of at least 0.2 – 0.4 ng/well of recombinant Human Neuroserpin.Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hNeuroserpin (human Neuroserpin). Anti-Human Neuroserpin specific antibody was purified by affinity chromatography and then biotinylated. | |
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| Conjugate | Biotin | |
| Clone | Polyclonal | |
| Target Species | Human | |
| Applications | ELISA, Capture, WB | |
| Supplier | PeproTech | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Neuroserpin
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
This gene encodes a member of the serpin superfamily of serine proteinase inhibitors. The protein is primarily secreted by axons in the brain, and preferentially reacts with and inhibits tissue-type plasminogen activator. It is thought to play a role in the regulation of axonal growth and the development of synaptic plasticity. Mutations in this gene result in familial encephalopathy with neuroserpin inclusion bodies (FENIB), which is a dominantly inherited form of familial encephalopathy and epilepsy characterized by the accumulation of mutant neuroserpin polymers. Multiple alternatively spliced variants, encoding the same protein, have been identified. [provided by RefSeq, Jul 2008]
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130 Neuroserpin antibodies from over 11 suppliers available with over 35 conjugates.
