Arginase 1 / Fluorescein /
Product Details
Description | Human/Mouse Arginase 1/ARG1 Fluorescein-conjugated Antibody | |
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Conjugate | Fluorescein | |
Clone | ||
Target Species | Human, Mouse | |
Applications | ICS | |
Supplier | R&D Systems | |
Catalog # | Sign in to view product details, citations, and spectra | |
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Antigen | ||
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About Arginase 1
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Arginase catalyzes the hydrolysis of arginine to ornithine and urea. At least two isoforms of mammalian arginase exist (types I and II) which differ in their tissue distribution, subcellular localization, immunologic crossreactivity and physiologic function. The type I isoform encoded by this gene, is a cytosolic enzyme and expressed predominantly in the liver as a component of the urea cycle. Inherited deficiency of this enzyme results in argininemia, an autosomal recessive disorder characterized by hyperammonemia. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
About Fluorescein
Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm.
Fluorescein is an organic fluorophore first synthesized by Aldolf Bayer in 1871. FITC, an amine-reactive derivative, is also a commonly used name for this dye. It has an excitation peak at 494 nm and an emission peak at 512 nm.
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Validation References
PMID 22522114 | |
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PMID 24196717 | |
PMID 24741628 | |
PMID 28107450 | |
PMID 28165503 | |
PMID 28275135 | |
PMID 29184069 | |
Additional Sources |
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