About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]

About PerCP-Fire 806
PerCP/Fire™ 806 is an innovative and unique flow cytometry fluorophore excited by the 488 nm blue laser that emits beyond 800 nm. It can be used on conventional cytometers with a 780/60 filter, but is optimal for spectral instruments with both blue and yellow/green lasers. This allows it to be unmixed from dyes like PE/Cyanine7 and PE/Fire™ 810. Its potent brightness makes it suitable for antigens with low expression levels.