CD4 / StarBright Blue 700 / RPA-T4

Product Details
Description Mouse Anti Human CD4:StarBright Blue 700
Conjugate StarBright Blue 700
Clone RPA-T4
Target Species Human
Applications FC
Supplier Bio-Rad
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About StarBright Blue 700
StarBright Blue 700 (SBB700) is a fluorescent polymer nanoparticle with an excitation peak at 475 nm and an emission peak at 700 nm, an alternative to PerCP-Cy5.5 in flow cytometry. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliantâ„¢ polymer series from BD Biosciences including Brilliantâ„¢ Violet and Brilliantâ„¢ UV. StarBright Blue 700 is spectrally comparable to BB700 and Nova Fluor Blue 690.
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