About CD27
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

About StarBright Yellow 720
StarBright Yellow 720 (SBY720) Dye is a bright 561 nm excitable dye with a unique and narrow emission. It can be used in place of PE-Cy5.5 and PE-A700 in multicolor panels as it is brighter, has reduced 488 nm excitation, and is fixable in PFA and alcohol-based buffers without loss of signal or changes to the spectra. Furthermore, as it is not a traditional tandem dye it is not prone to changes in emission over time due to acceptor and donor uncoupling, giving you reproducible data. Like all StarBright Dyes, SBY720 can be multiplexed with other StarBright Dyes or other fluorophores without the need for a special buffer and can be premixed in a panel and stored at 4⁰C for over a month without changes to staining.