About CD27
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-kappaB and MAPK8/JNK. Adaptor proteins TRAF2 and TRAF5 have been shown to mediate the signaling process of this receptor. CD27-binding protein (SIVA), a proapoptotic protein, can bind to this receptor and is thought to play an important role in the apoptosis induced by this receptor. [provided by RefSeq, Jul 2008]

About StarBright Blue 810
StarBright Blue 810 (SBB810) Dye is a bright, 488 nm laser excitable dye with a unique narrow excitation and emission profile and is suitable for conventional and full spectrum flow cytometry. It is brighter than PE-Cy7 when excited by the 488 nm laser. As it is not a traditional tandem dye, SBB810 does not have issues around tandem breakdown and changes to staining over time and exhibits reduced excitation by the 561 nm laser compared to PE tandem dyes. SBB810 provides more choice and flexibility when building multicolor panels incorporating the 488 nm laser.