CD11b / StarBright Blue 615 / 5C6

Product Details
Description Rat anti Mouse CD11b:StarBright Blue 615
Conjugate StarBright Blue 615
Clone 5C6
Target Species Mouse
Applications FC
Supplier Bio-Rad
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About StarBright Blue 615
StarBright Blue 615 (SBB615) Dye is a bright, 488 nm laser excitable dye with a unique, narrow excitation and emission profile and is suitable for conventional and full spectrum flow cytometry. It is brighter than PE-CF594 and PE-Dazzle594 when excited by the 488 nm and is not excited to the same degree by the 561 nm laser. As it is not a traditional tandem dye, SBB615 does not have issues around tandem breakdown and changes to staining over time. SBB615 provides more choice and flexibility when building multicolor panels incorporating the 488 nm laser.
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