About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

About StarBright Blue 580
StarBright Blue 580 (SBB580) Dye is a bright, 488 nm laser excitable dye with a unique narrow excitation and emission profile and is suitable for conventional and full spectrum flow cytometry. It is brighter than other 488 nm laser excitable dyes such as AF532 and is as bright as PE when excited by the 488 nm laser. It has the added benefit of having reduced excitation by the 561 nm laser compared with PE. SBB580 and PE are compatible in a panel when using both the 488 and 561 nm lasers to excite each respective dye. This provides more choice and flexibility when building multicolor panels.