CD8a / StarBright Blue 810 / KT15

Product Details
Description Rat anti Mouse CD8 Alpha:StarBright Blue 810
Conjugate StarBright Blue 810
Clone KT15
Target Species Mouse
Applications FC
Supplier Bio-Rad
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About CD8a
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
About StarBright Blue 810
StarBright Blue 810 (SBB810) Dye is a bright, 488 nm laser excitable dye with a unique narrow excitation and emission profile and is suitable for conventional and full spectrum flow cytometry. It is brighter than PE-Cy7 when excited by the 488 nm laser. As it is not a traditional tandem dye, SBB810 does not have issues around tandem breakdown and changes to staining over time and exhibits reduced excitation by the 561 nm laser compared to PE tandem dyes. SBB810 provides more choice and flexibility when building multicolor panels incorporating the 488 nm laser.
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