CD4 / StarBright Blue 615 / RM4-5
Product Details
Description | Rat anti Mouse CD4:StarBright Blue 615 | |
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Conjugate | StarBright Blue 615 | |
Clone | RM4-5 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Bio-Rad | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About StarBright Blue 615
StarBright Blue 615 (SBB615) Dye is a bright, 488 nm laser excitable dye with a unique, narrow excitation and emission profile and is suitable for conventional and full spectrum flow cytometry. It is brighter than PE-CF594 and PE-Dazzle594 when excited by the 488 nm and is not excited to the same degree by the 561 nm laser. As it is not a traditional tandem dye, SBB615 does not have issues around tandem breakdown and changes to staining over time. SBB615 provides more choice and flexibility when building multicolor panels incorporating the 488 nm laser.
StarBright Blue 615 (SBB615) Dye is a bright, 488 nm laser excitable dye with a unique, narrow excitation and emission profile and is suitable for conventional and full spectrum flow cytometry. It is brighter than PE-CF594 and PE-Dazzle594 when excited by the 488 nm and is not excited to the same degree by the 561 nm laser. As it is not a traditional tandem dye, SBB615 does not have issues around tandem breakdown and changes to staining over time. SBB615 provides more choice and flexibility when building multicolor panels incorporating the 488 nm laser.
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