CD4 / MultiDot 575 / RPA-T4

Product Details
Description MultiDot 575 nm CD4 (RPAT4) – 25 Tests
Conjugate MultiDot 575
Clone RPA-T4
Target Species Human
Applications FC
Supplier Core Quantum Technologies
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About MultiDot 575
MultiDot 575 is a yellow emitting fluorophore optimally excited from 320 nm to 405 nm with an emission peak at 580 nm. This dye is part of Core Quantum Technologies' MultiDot product line. Each MultiDot consists of several quantum dots with a patented coating, resulting in increased sensitivity and a tighter emission spectrum which limits spectral overlap.
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