CD44 / RealYellow 586 / IM7
Product Details
Description | RY586 Rat Anti-Mouse CD44 | |
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Conjugate | RealYellow 586 | |
Clone | IM7 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | BD Biosciences | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD44
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis. [provided by RefSeq, Jul 2008]
About RealYellow 586
BD Horizon RealYellow 586 (RY586) is a bright, yellow emitting dye used in flow cytometry. This fluorophore is excited optimally by the 561 laser and is similar in its emission properties to PE, but interestingly, RY586 shows minimal cross-laser excitation with the 488 laser and can be used in spectral flow cytometry panels concurrently with PE (as stated by supplier).
BD Horizon RealYellow 586 (RY586) is a bright, yellow emitting dye used in flow cytometry. This fluorophore is excited optimally by the 561 laser and is similar in its emission properties to PE, but interestingly, RY586 shows minimal cross-laser excitation with the 488 laser and can be used in spectral flow cytometry panels concurrently with PE (as stated by supplier).
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