CD49e / RealBlue 780 / IIA1
Product Details
Description | RB780 Mouse Anti-Integrin alpha5 chain (CD49e) | |
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Conjugate | RealBlue 780 | |
Clone | IIA1 | |
Target Species | Human | |
Applications | FC | |
Supplier | BD Biosciences | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD49e
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
The product of this gene belongs to the integrin alpha chain family. Integrins are heterodimeric integral membrane proteins composed of an alpha subunit and a beta subunit that function in cell surface adhesion and signaling. The encoded preproprotein is proteolytically processed to generate light and heavy chains that comprise the alpha 5 subunit. This subunit associates with the beta 1 subunit to form a fibronectin receptor. This integrin may promote tumor invasion, and higher expression of this gene may be correlated with shorter survival time in lung cancer patients. Note that the integrin alpha 5 and integrin alpha V subunits are encoded by distinct genes. [provided by RefSeq, Oct 2015]
About RealBlue 780
BD Horizon RealBlue™ 780 (RB780) is part of BD's new product line of laser-specific fluorochromes which are designed to minimize cross laser excitaiton. This fluorochrome has a maximum excitation wavelength of 488nm and a maximum emission wavelength of 780nm. While RB780 is excited by the 488nm blue laser, it offers miminal cross-laser excitation off of the 561nm yellow/green laser. It is designed for use in Flow Cytometry and Spectral Flow Cytometry.
BD Horizon RealBlue™ 780 (RB780) is part of BD's new product line of laser-specific fluorochromes which are designed to minimize cross laser excitaiton. This fluorochrome has a maximum excitation wavelength of 488nm and a maximum emission wavelength of 780nm. While RB780 is excited by the 488nm blue laser, it offers miminal cross-laser excitation off of the 561nm yellow/green laser. It is designed for use in Flow Cytometry and Spectral Flow Cytometry.
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