About CD43
This gene encodes a highly sialylated glycoprotein that functions in antigen-specific activation of T cells, and is found on the surface of thymocytes, T lymphocytes, monocytes, granulocytes, and some B lymphocytes. It contains a mucin-like extracellular domain, a transmembrane region and a carboxy-terminal intracellular region. The extracellular domain has a high proportion of serine and threonine residues, allowing extensive O-glycosylation, and has one potential N-glycosylation site, while the carboxy-terminal region has potential phosphorylation sites that may mediate transduction of activation signals. Different glycoforms of this protein have been described. In stimulated immune cells, proteolytic cleavage of the extracellular domain occurs in some cell types, releasing a soluble extracellular fragment. Defects in expression of this gene are associated with Wiskott-Aldrich syndrome. [provided by RefSeq, Sep 2017]

About RealYellow 586
BD Horizon RealYellow 586 (RY586) is a bright, yellow emitting dye used in flow cytometry. This fluorophore is excited optimally by the 561 laser and is similar in its emission properties to PE, but interestingly, RY586 shows minimal cross-laser excitation with the 488 laser and can be used in spectral flow cytometry panels concurrently with PE (as stated by supplier).