CD161 / RealBlue 780 / DX12

Product Details
Description RB780 Mouse Anti-Human CD161 (KLRB1)
Conjugate RealBlue 780
Clone DX12
Target Species Human
Applications FC
Supplier BD Biosciences
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About CD161
Natural killer (NK) cells are lymphocytes that mediate cytotoxicity and secrete cytokines after immune stimulation. Several genes of the C-type lectin superfamily, including the rodent NKRP1 family of glycoproteins, are expressed by NK cells and may be involved in the regulation of NK cell function. The KLRB1 protein contains an extracellular domain with several motifs characteristic of C-type lectins, a transmembrane domain, and a cytoplasmic domain. The KLRB1 protein is classified as a type II membrane protein because it has an external C terminus. [provided by RefSeq, Jul 2008]
About RealBlue 780
BD Horizon RealBlue™ 780 (RB780) is part of BD's new product line of laser-specific fluorochromes which are designed to minimize cross laser excitaiton. This fluorochrome has a maximum excitation wavelength of 488nm and a maximum emission wavelength of 780nm. While RB780 is excited by the 488nm blue laser, it offers miminal cross-laser excitation off of the 561nm yellow/green laser. It is designed for use in Flow Cytometry and Spectral Flow Cytometry.
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