Tau / PE / REAL1291

Product Details

Description	Clone REAL1291 is an antibody fragment derived from the full Tau antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. \| Clone REAL1291 recognizes the antigen Tau, a protein expressed in neurons. Tau belongs to the family of microtubule-associated proteins (MAPs), whose members interact with the microtubules of the cellular cytoskeleton and have different functions. The binding of MAPs to tubulin dimers of microtubules leads to the stabilization of microtubule structure. \| For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). \|
Conjugate	PE
Clone	REAL1291
Target Species	Human
Applications	MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier	Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

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