CLEC2a / Vio Bright V423 / REA544

Product Details
Description Clone REA544 recognizes the human CLEC2A antigen, which is a member of the C-type lectin-like domain–containing family. It enhances TCR-stimulated T cell expansion by upregulating anti-apoptotic proteins and may modulate the capacity of T cells to home to lymph nodes through SELL. It facilitates dedicated immune recognition of keratinocytes via interaction with its receptor KLRF2 by stimulating natural killer cell mediated cytotoxicity. In contrast to the other CLEC2 family members AICL, CD69, and LLT1, CLEC2A is predominantly expressed in skin. | Additional information: Clone REA544 displays negligible binding to Fc receptors.
Conjugate Vio Bright V423
Clone REA544
Target Species Human
Applications FC
Supplier Miltenyi Biotec
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About Vio Bright V423
Vio® Bright V423 is a very bright Violet emitting synthetic fluorophore used in flow cytometry. The excitation and emission peaks are 399 nm and 420 nm, respectively, which means that this dye is optimally excited by the 405 nm Violet laser while the emission light is collected by a 450/50 bandpass filter.
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