TNF alpha / DyLight 488 / TN3-19.12
Product Details
| Description | TNF-alpha is a 17.5 kD protein that mediates inflammation and immunity caused by the invasion of viruses, bacteria, and parasites by initiating a cascade of cytokines that increase vascular permeability, thus bringing macrophages and neutrophils to the site of infection. TNF-alpha secreted by the macrophage causes the blood to clot which provides containment of the infection. TNF-alpha binding to surface receptors brings about various biologic activities that include cytolysis and cytostasis of many tumor cell lines In vitro, hemorraghic necrosis of tumors In vivo, increased fibroblast proliferation, and enhanced chemotaxis and phagocytosis in neutrophils. | |
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| Conjugate | DyLight 488 | |
| Clone | TN3-19.12 | |
| Target Species | Mouse | |
| Applications | FC | |
| Supplier | Leinco | |
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About DyLight 488
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
DyLight™ 488 has an excitation peak at 493 nm and an emission peak at 518 nm and is spectrally similar to Alexa Fluor™ 488, fluorescein and FITC. DyLight™ 488 is most commonly used in flow cytometery, and fluorescence microscopy applications.
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2470 TNF alpha antibodies from over 43 suppliers available with over 83 conjugates.
