SIGIRR / Unconjugated /
Product Details
| Description | Single immunoglobulin and toll-interleukin 1 receptor (TIR) domain, also known as SIGIRR is a member of the IL-1 receptor family.1 It acts as a negative regulator of interleukin (IL)-1 and lipopolysaccharide (LPS) signaling.2 It also plays a critical role in gut homeostasis, intestinal inflammation, and colitis-associated tumorigenesis by maintaining the microbial tolerance of the colonic epithelium.3 | |
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| Conjugate | Unconjugated | |
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| Target Species | Mouse | |
| Applications | WB | |
| Supplier | Leinco | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About SIGIRR
Predicted to enable NAD+ nucleosidase activity. Involved in negative regulation of DNA-binding transcription factor activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
Predicted to enable NAD+ nucleosidase activity. Involved in negative regulation of DNA-binding transcription factor activity. Located in membrane. [provided by Alliance of Genome Resources, Apr 2022]
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258 SIGIRR antibodies from over 15 suppliers available with over 37 conjugates.
