CD16 / APC / 3G8
Product Details
| Description | CD16 antibody, 3G8, recognizes human CD16, also known as low-affinity IgG receptor III (FcgammaRIII). There are two distinct forms of CD16, CD16a (FcgammaRIIIa) and CD16b (FcgammaRIIIb). CD16a is a 50-65 kDa heterooligomeric polypeptide-anchored transmembrane protein expressed by NK cells, macrophages, and subsets of monocytes1. CD16b is a 48 kDa monomeric glycosylphosphatidylinositol (GPI)-anchored protein expressed on neutrophils1. Upon binding to the Fc portion of IgG or IgG-antigen complex, both CD16 isoforms induce signaling cascades resulting in multiple functions, including phagocytosis, cytokine release, proliferation, degranulation, and antibody dependent cell-mediated cytotoxicity (ADCC)2. | |
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| Conjugate | APC | |
| Clone | 3G8 | |
| Target Species | Baboon, Chimpanzee, Cynomolgus, Human, Marmoset, Pigtailed Macaque, Rhesus, Squirrel Monkey | |
| Applications | FC | |
| Supplier | Leinco | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About APC
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
Allophycocyanin (APC) is a fluorescent protein derived from cyanobacteria and red algae and a potent donor fluorophore to create tandem dyes that can be excited off the 633-640 nm laser. APC has an excitation peak at 650 nm and a emission peak at 660 nm.
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1972 CD16 antibodies from over 49 suppliers available with over 149 conjugates.
