CD91 / NovaFluor Yellow 730 / A2MR-a2

Product Details
Description CD91 Monoclonal Antibody (A2MR-a2), NovaFluor Yellow 730, eBioscience
Conjugate NovaFluor Yellow 730
Clone A2MR-a2
Target Species Mouse
Applications FC
Supplier Thermo Fisher Scientific
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About CD91
This gene encodes a member of the low-density lipoprotein receptor family of proteins. The encoded preproprotein is proteolytically processed by furin to generate 515 kDa and 85 kDa subunits that form the mature receptor (PMID: 8546712). This receptor is involved in several cellular processes, including intracellular signaling, lipid homeostasis, and clearance of apoptotic cells. In addition, the encoded protein is necessary for the alpha 2-macroglobulin-mediated clearance of secreted amyloid precursor protein and beta-amyloid, the main component of amyloid plaques found in Alzheimer patients. Expression of this gene decreases with age and has been found to be lower than controls in brain tissue from Alzheimer's disease patients. [provided by RefSeq, Oct 2015]
About NovaFluor Yellow 730
The NovaFluor family of fluorescent polymers from Thermo Fisher Scientific are a novel reagent for traditional and spectral flow cytometry. These fluorophores are comprised of a DNA backbone polymer integrated with fluorophore substituted nucleosides to create a potent donor molecule. Tandem fluophores with long Stokes' Shift enable brighter, spectrally discrete, tunable fluorescent polymers as an alternative to traditional simple organic structures, protein-based fluorophores as well as the Horizon Brilliantâ„¢ family of fluorescent polymers from BD. NovaFluor Yellow 730 is designed to be discreetly excited by the 561nm laser and has an excitation peak at 552 nm and an emission peak at 730 nm.
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