TNF alpha / PE-Vio770 / REA656

Product Details

Description	Clone REA656 recognizes the human tumor necrosis factor alpha (TNF-alpha) antigen, which is a cytokine involved in inflammatory immune responses. TNF-alpha has different functions, it plays an important role in the regulation of immune cells and is a potent pyrogen causing fever and apoptotic cell death. Furthermore, the TNF intracellular domain form is able to induce interleukin 12 (IL-12) production in dendritic cells. TNF-alpha is secreted by activated CD4+ T cells, monocytes, macrophages, natural killer (NK) cells, mast cells, eosinophils, and neutrophils. \| Additional information: Clone REA656 displays negligible binding to Fc receptors.
Conjugate	PE-Vio770
Clone	REA656
Target Species	Human
Applications	FC
Supplier	Miltenyi Biotec
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About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.

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