CD66a/c/e / PE / REAL1206

Product Details

Description	Clone REAL1206 is an antibody fragment derived from the full CD66ace antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. \| Clone REAL1206 recognizes the a, c and e epitopes of the human CD66 antigen. CD66 constitutes a gene family whose members belong to the Ig superfamily of carcinoembryonic antigens (CEA). They are involved in a wide variety of physiological processes such as embryonic development, pregnancy, bile transport, as well as pathological conditions such as cancer, bacterial or viral infection, and inflammation. CD66a (CEACAM1), CD66c (CEACAM6), and CD66e (CEACAM5) are differentially expressed on some epithelial cells as well as on T cells, NK cell subsets, and granulocytes, especially neutrophils. \| For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675). \|
Conjugate	PE
Clone	REAL1206
Target Species	Human
Applications	MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier	Miltenyi Biotec
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About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

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