CD184 / PE-Vio770 / REA107

Product Details

Description	Clone REA107 reacts with CD184, a receptor for C-X-C chemokine CXCL12/SDF-1. CD184 is a seven membrane spanning receptor and belongs to the family of G-protein coupled chemokine receptors. Expression of CD184 is found in tissues including spleen, thymus, bone marrow, lymph nodes, and at lower levels in small intestine, kidney, and stomach. Diverse functions of CD184 include promoting survival and proliferation of hematopoietic stem cells, inducing apoptosis in T cells, regulating osteoclastogenesis, B cell development, vascularization of the gastrointestinal tract, germ cell migration/survival, and cerebellar development. CD184 also serves as a co-receptor for entry into target cells by HIV-1 X4 and interacts with extracellular ubiquitin. \| Additional information: Clone REA107 displays negligible binding to Fc receptors. \|
Conjugate	PE-Vio770
Clone	REA107
Target Species	Mouse
Applications	FC
Supplier	Miltenyi Biotec
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About PE-Vio770
PE-Vio® 770 from Miltenyi Biotec is a red-emitting tandem fluorophore that combines pycoerythrin (PE) and Vio®770. The donor molecule, PE can be excited by the 488-nm blue, 532-nm green, or 561-nm yellow-green laser and and transfers energy to the acceptor molecule, Vio®770, which emitts light that can be captured with a 780/60 nm bandpass filter. PE-Vio®770 has an excitation peak at 565 nm and an emission peak at 775 nm and is a common alternative to PE-Cy7 and PE-H7.

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