pan actin / PE / REAL563

Product Details

Description	Clone REAL563 is an antibody fragment derived from the full Pan-Actin antibody molecule. It displays no binding to Fc receptors. The recombinantly engineered antibody fragments are multimerized to form the REAdye_lease Complex to bind markers with high avidity. \| Clone REAL563 recognizes Pan-Actin, which is the major component of the cytoskeleton. Actin is a family of globular multi-functional proteins that form microfilaments that are essential components of the eukaryotic cytoskeleton. It is involved in many processes, e.g. in the establishment and maintenance of cell junctions and cell shape, muscle contraction, cell motility, cell division and cytokinesis, vesicle and organelle movement, and cell signaling. Mutations of this gene lead to several illnesses and diseases. \| For removal of REAdye_lease fluorochromes for optional relabeling with different fluorochrome-conjugated REAdye_lease antibodies use the REAlease Support Kit (130-120-675).
Conjugate	PE
Clone	REAL563
Target Species	Human
Applications	MICS (MACSima Imaging Cyclic Staining), IF, IHC
Supplier	Miltenyi Biotec
	Catalog #	Sign in to view product details, citations, and spectra
	Size
	Price
	Antigen
	Host
	Isotype

About PE
Phycoerythrin (PE, R-PE) is a red-emitting fluorescent protein-chromophore complex that can be excited the 488-nm blue, 532-nm green, or 561-nm yellow-green laser with increasing efficiency and captured with a 586/14 nm bandpass filter. PE has an excitation peak at 565 nm and an emission peak at 578 nm. PE is 240kD in size and has an extinction coefficient of ~2x10^6 which makes it one of the brightest fluorophores available and a potent donor upon which to build tandem fluorophores with longer Stoke's Shifts.

Experiment Design Tools