Mineralocorticoid Receptor / Biotin / H10E4C9F
Product Details
Description | Mineralocorticoid R/NR3C2 Antibody (H10E4C9F) [Biotin] | |
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Conjugate | Biotin | |
Clone | H10E4C9F | |
Target Species | Chicken, Human, Mouse, Rabbit, Rat, Sheep | |
Applications | FC, ICC, IF, IHC-P, WB, IHC | |
Supplier | Novus Biologicals | |
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About Mineralocorticoid Receptor
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
This gene encodes the mineralocorticoid receptor, which mediates aldosterone actions on salt and water balance within restricted target cells. The protein functions as a ligand-dependent transcription factor that binds to mineralocorticoid response elements in order to transactivate target genes. Mutations in this gene cause autosomal dominant pseudohypoaldosteronism type I, a disorder characterized by urinary salt wasting. Defects in this gene are also associated with early onset hypertension with severe exacerbation in pregnancy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
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