CD11b / Spark Blue 550 / M1/70
Product Details
Description | Spark Blue™ 550 anti-mouse/human CD11b | |
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Conjugate | Spark Blue 550 | |
Clone | M1/70 | |
Target Species | Baboon, Chimpanzee, Cynomolgus, Human, Mouse, Rabbit, Rhesus | |
Applications | FC | |
Supplier | BioLegend | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About Spark Blue 550
Spark Blue™ 550 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 516 nm and an emission peak at 540 nm. This fluorophore is an alternative to Alexa Fluor™ 532 and can be efficiently excited by the 488 nm laser and can be unmixed from FITC and PE.
Spark Blue™ 550 from Biolegend is a fluorophore designed for spectral flow cytometry with an excitation peak at 516 nm and an emission peak at 540 nm. This fluorophore is an alternative to Alexa Fluor™ 532 and can be efficiently excited by the 488 nm laser and can be unmixed from FITC and PE.
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