p57Kip2 / DyLight 755 / KIP2/7083R

Product Details
Description p57 Kip2 Antibody (KIP2/7083R) [DyLight 755]
Conjugate DyLight 755
Clone KIP2/7083R
Target Species Human, Mouse
Applications IHC-P, IHC
Supplier Novus Biologicals
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About p57Kip2
This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2010]
About DyLight 755
DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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