MDM2 / DyLight 680 / MDM2/7061R

Product Details
Description MDM2/HDM2 Antibody (MDM2/7061R) [DyLight 680]
Conjugate DyLight 680
Clone MDM2/7061R
Target Species Human
Applications ELISA
Supplier Novus Biologicals
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About MDM2
This gene encodes a nuclear-localized E3 ubiquitin ligase. The encoded protein can promote tumor formation by targeting tumor suppressor proteins, such as p53, for proteasomal degradation. This gene is itself transcriptionally-regulated by p53. Overexpression or amplification of this locus is detected in a variety of different cancers. There is a pseudogene for this gene on chromosome 2. Alternative splicing results in a multitude of transcript variants, many of which may be expressed only in tumor cells. [provided by RefSeq, Jun 2013]
About DyLight 680
DyLight™ 680 has an excitation peak at 692 nm and an emission peak at 712 nm, and is spectrally similar to Alexa Fluor™ 680 and Cy5.5. DyLight™ 680 is most commonly used in flow cytometery and fluorescence microscopy applications.
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