HDAC3 / DyLight 755 / PCRP-HDAC3-3C9

Product Details
Description HDAC3 Antibody (PCRP-HDAC3-3C9) [DyLight 755]
Conjugate DyLight 755
Clone PCRP-HDAC3-3C9
Target Species Human
Applications ELISA, FC, ICC, IF, WB
Supplier Novus Biologicals
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About HDAC3
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq, Jul 2008]
About DyLight 755
DyLight™ 755 has an excitation peak of 754 nm and an emission peak of 776 nm and is spectrally similar to Alexa Fluor™ 750. DyLight™ 755 is most commonly used in fluorescence micrscopy.
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