CD11b / Spark UV 387 / ICRF44
Product Details
| Description | Spark UV™ 387 anti-human CD11b Antibody | |
|---|---|---|
| Conjugate | Spark UV 387 | |
| Clone | ICRF44 | |
| Target Species | African Green Monkey, Baboon, Chimpanzee, Common Marmoset, Cynomolgus, Human, Porcine, Rhesus | |
| Applications | FC | |
| Supplier | BioLegend | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About Spark UV 387
Spark UV® 387 from Biolegend is a fluorophore with an excitation peak at 351 nm and an emission peak at 387 nm. This fluorophore is an alternative to Alexa Fluor™ 350 and can be excited by the 355 nm laser.
Spark UV® 387 from Biolegend is a fluorophore with an excitation peak at 351 nm and an emission peak at 387 nm. This fluorophore is an alternative to Alexa Fluor™ 350 and can be excited by the 355 nm laser.
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