CD4 / NovaFluor Blue 610 / 70S / OKT4

Product Details
Description CD4 Monoclonal Antibody (OKT4 (OKT-4)), NovaFluor™ Blue 610-70S, eBioscience™
Conjugate NovaFluor Blue 610 / 70S
Clone OKT4
Target Species Human
Applications FC
Supplier Thermo Fisher Scientific
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About CD4
This gene encodes the CD4 membrane glycoprotein of T lymphocytes. The CD4 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class II MHC molecules. The CD4 antigen is also a primary receptor for entry of the human immunodeficiency virus through interactions with the HIV Env gp120 subunit. This gene is expressed not only in T lymphocytes, but also in B cells, macrophages, granulocytes, as well as in various regions of the brain. The protein functions to initiate or augment the early phase of T-cell activation, and may function as an important mediator of indirect neuronal damage in infectious and immune-mediated diseases of the central nervous system. Multiple alternatively spliced transcript variants encoding different isoforms have been identified in this gene. [provided by RefSeq, May 2020]
About NovaFluor Blue 610 / 70S
The NovaFluor family of fluorescent polymers from Thermo Fisher Scientific are a novel reagent for traditional and spectral flow cytometry. These fluorophores are comprised of a DNA backbone polymer integrated with fluorophore substituted nucleosides to create a potent donor molecule. Tandem fluophores with long Stokes' Shift enable brighter, spectrally discrete, tunable fluorescent polymers as an alternative to traditional simple organic structures, protein-based fluorophores as well as the Horizon Brilliant™ family of fluorescent polymers from BD. NovaFluor Blue 610/70S is designed to be discreetly excited by the 488 nm laser and has an excitation peak at 496 nm and an emission peak at 614 nm. NovaFluor Blue 610/ 70S is bigger and brighter than NovaFluor Blue 610/ 30S.
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