CD11b / NovaFluor Yellow 570 / ICRF44

Product Details
Description CD11b Monoclonal Antibody (ICRF44), NovaFluor™ Yellow 570, eBioscience™
Conjugate NovaFluor Yellow 570
Clone ICRF44
Target Species Baboon, Chimpanzee, Cynomolgus, Human, Rhesus
Applications FC
Supplier Thermo Fisher Scientific
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About NovaFluor Yellow 570
The NovaFluor family of fluorescent polymers from Thermo Fisher Scientific are a novel reagent for traditional and spectral flow cytometry. These fluorophores are comprised of a DNA backbone polymer integrated with fluorophore substituted nucleosides to create a potent donor molecule. Tandem fluophores with long Stokes' Shift enable brighter, spectrally discrete, tunable fluorescent polymers as an alternative to traditional simple organic structures, protein-based fluorophores as well as the Horizon Brilliant™ family of fluorescent polymers from BD. NovaFluor Yellow 570 is designed to be discreetly excited by the 561nm laser and has an excitation peak at 552 nm and an emission peak at 568 nm.
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