About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]

About APC-Fire 810
APC-Fire™ 810 from BioLegend has an excitation peak at 650nm and an emission peak at 807 nm and is spectrally similar to APC-CF®790. APC-Fire™ 810 is most commonly used in flow cytometry. On a 5-laser Cytek® Aurora, it has very limited spectral spillover into any other channel, so it can be assigned to any antigen with moderate to abundant expression and used in combination with any other fluorophore. This dye is very useful for detecting variably expressed markers, like markers of activation, since it emits so far outside of the autofluorescence range.