CD8a / StarBright UltraViolet 445 / KT15
Product Details
Description | RAT ANTI MOUSE CD8 ALPHA:StarBright UltraViolet 445 | |
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Conjugate | StarBright UltraViolet 445 | |
Clone | KT15 | |
Target Species | Mouse | |
Applications | FC | |
Supplier | Bio-Rad | |
Catalog # | Sign in to view product details, citations, and spectra | |
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About CD8a
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. The major protein isoforms of this gene differ by the presence or absence of a transmembrane domain and thus differ in being a membrane-anchored or secreted protein. [provided by RefSeq, May 2020]
About StarBright UltraViolet 445
StarBright UltraViolet 445 (SBUV445) is a fluorescent polymer nanoparticle that has an excitation peak at 347 nm and an emission peak at 440 nm, making it spectrally unique for spectral flow cytometry. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliantâ„¢ polymer series from BD Biosciences. StarBright UV 445 is spectrally unique.
StarBright UltraViolet 445 (SBUV445) is a fluorescent polymer nanoparticle that has an excitation peak at 347 nm and an emission peak at 440 nm, making it spectrally unique for spectral flow cytometry. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliantâ„¢ polymer series from BD Biosciences. StarBright UV 445 is spectrally unique.
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