MSH3 / Unconjugated / RM405
Product Details
| Description | RABBIT ANTI MSH3 | |
|---|---|---|
| Conjugate | Unconjugated | |
| Clone | RM405 | |
| Target Species | Human | |
| Applications | IHC-P, WB | |
| Supplier | Bio-Rad | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About MSH3
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
The protein encoded by this gene forms a heterodimer with MSH2 to form MutS beta, part of the post-replicative DNA mismatch repair system. MutS beta initiates mismatch repair by binding to a mismatch and then forming a complex with MutL alpha heterodimer. This gene contains a polymorphic 9 bp tandem repeat sequence in the first exon. The repeat is present 6 times in the reference genome sequence and 3-7 repeats have been reported. Defects in this gene are a cause of susceptibility to endometrial cancer. [provided by RefSeq, Mar 2011]
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144 MSH3 antibodies from over 17 suppliers available with over 26 conjugates.
