About CD25
The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with interleukin 2 receptor alpha deficiency. Patients with severe Coronavirus Disease 2019 (COVID-19), the disease caused by the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have significantly elevated levels of IL2R in their plasma. Similarly, serum IL-2R levels are found to be elevated in patients with different types of carcinomas. Certain IL2RA and IL2RB gene polymorphisms have been associated with lung cancer risk. [provided by RefSeq, Jul 2020]

About StarBright UltraViolet 400
StarBright UltraViolet 400 (SBUV400) is a fluorescent polymer nanoparticle that has an excitation peak at 347 nm and an emission peak at 394 nm, an alternative to BUV495 in flow cytometry. The StarBright family fluorophores from Bio-Rad offers an alternative to the Horizon Brilliant™ polymer series from BD Biosciences including Brilliant™ Violet and Brilliant™ UV. StarBright UV 400 is spectrally equivalent to BUV395.