CD11b / Amethyst Orange / 5C6

Product Details
Description RAT ANTI MOUSE CD11b:Amethyst Orange
Conjugate Amethyst Orange
Clone 5C6
Target Species Human, Mouse
Applications FC
Supplier Bio-Rad
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About CD11b
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
About Amethyst Orange
Amethyst Orange from Bio-Rad has an excitation peak at 390 nm and an emission peak at 535 nm. It can be excited by the 405 nm laser on a flow cytometer and is spectrally most similar to Pacific Orange. However, StarBright Violet 515 and StarBright Violet 570 both offer brighter alternatives for that emission range in flow cytometry.
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