Desmoglein-3 / Unconjugated / 5G11

Product Details
Description Anti desmoglein-3 [5G11]
Conjugate Unconjugated
Clone 5G11
Target Species Human
Applications FC, IF, WB, IP, IHC, Dot Blot
Supplier Absolute Antibody
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About Desmoglein-3
This gene encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. This gene is present in a gene cluster with other desmoglein gene family members on chromosome 18. The encoded protein has been identified as the autoantigen of the autoimmune blistering disease pemphigus vulgaris. [provided by RefSeq, Jan 2016]
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