Complement Factor D / Unconjugated / I8/1

Product Details
Description Anti Complement Factor D [I8/1]
Conjugate Unconjugated
Clone I8/1
Target Species Human
Applications ELISA, WB
Supplier Absolute Antibody
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About Complement Factor D
This gene encodes a member of the S1, or chymotrypsin, family of serine peptidases. This protease catalyzes the cleavage of factor B, the rate-limiting step of the alternative pathway of complement activation. This protein also functions as an adipokine, a cell signaling protein secreted by adipocytes, which regulates insulin secretion in mice. Mutations in this gene underlie complement factor D deficiency, which is associated with recurrent bacterial meningitis infections in human patients. Alternative splicing of this gene results in multiple transcript variants. At least one of these variants encodes a preproprotein that is proteolytically processed to generate the mature protease. [provided by RefSeq, Nov 2015]
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