C-Myc / DyLight 350 / 2270A

Product Details
Description c-Myc Antibody (2270A) [DyLight 350]
Conjugate DyLight 350
Clone 2270A
Target Species Human
Applications Intracellular Staining by FC, Knockout Validated, ICC, WB
Supplier Novus Biologicals
Catalog # Sign in to view product details, citations, and spectra
Size
Price
Antigen
Host
Isotype
About C-Myc
This gene is a proto-oncogene and encodes a nuclear phosphoprotein that plays a role in cell cycle progression, apoptosis and cellular transformation. The encoded protein forms a heterodimer with the related transcription factor MAX. This complex binds to the E box DNA consensus sequence and regulates the transcription of specific target genes. Amplification of this gene is frequently observed in numerous human cancers. Translocations involving this gene are associated with Burkitt lymphoma and multiple myeloma in human patients. There is evidence to show that translation initiates both from an upstream, in-frame non-AUG (CUG) and a downstream AUG start site, resulting in the production of two isoforms with distinct N-termini. [provided by RefSeq, Aug 2017]
About DyLight 350
DyLight™ 350 has an excitation peak of 353 nm and an emission peak of 432 nm. It is spectrally similar to Alexa Fluor™ 350, iFluor® 350, AMCA, and Thioflavin T. DyLight™ 350 is most commonly used in flow cytometery and fluorescence microscopy applications.
Experiment Design Tools
Panel Builders

Looking to design a Microscopy or Flow Cytometry experiment?

Validation References
Additional
Sources
Reviews & Ratings
Looking for more options?

1810 C-Myc antibodies from over 43 suppliers available with over 66 conjugates.

Supplier Page
 Compare