CD14 Monoclonal / Alexa Fluor 488 / M5E2

Product Details
Description Alexa Fluor 488 anti-human CD14
Conjugate Alexa Fluor 488
Clone M5E2
Target Species Bovine, Canine, Capuchin Monkey, Chimpanzee, Common Marmoset, Cotton-topped Tamarin, Cynomolgus, Human, Pigtailed Macaque, Rhesus, Squirrel Monkey
Applications FC
Supplier Sony
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About CD14
The protein encoded by this gene is a surface antigen that is preferentially expressed on monocytes/macrophages. It cooperates with other proteins to mediate the innate immune response to bacterial lipopolysaccharide, and to viruses. This gene has been identified as a target candidate in the treatment of SARS-CoV-2-infected patients to potentially lessen or inhibit a severe inflammatory response. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq, Aug 2020]
About Alexa Fluor 488
Alexa Fluor™ 488 (AF488, Alexa 488) has an excitation peak at 488 nm and an emission peak at 496 nm, and is considered a high-performance alternative to FITC. Alexa 488 is one of the most popular Alexa Fluor™ dyes and is widely used in Fluorescence Microscopy, flow cytometry, and for staining low expression markers. It is bright, highly photostable, resistant to pH changes, and less susceptible to photobleaching. Alexa 488 and is similar in size, brightness and application to DyLight™ 488, iFluor® 488 and CF®488A.
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