Insulin / eFluor 660 / CBYY-I0257
Product Details
| Description | This product is Mouse antibody that recognizes INS. The antibody CBYY-I0257 can be used for immunoassay techniques such as: IHC-P, WB, ICC, IF | |
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| Conjugate | eFluor 660 | |
| Clone | CBYY-I0257 | |
| Target Species | Human, Mouse, Rat | |
| Applications | Purification, IF, ICC, WB | |
| Supplier | Creative Biolabs | |
| Catalog # | Sign in to view product details, citations, and spectra | |
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About Insulin
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020]
This gene encodes insulin, a peptide hormone that plays a vital role in the regulation of carbohydrate and lipid metabolism. After removal of the precursor signal peptide, proinsulin is post-translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C-peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified, including insulin-dependent diabetes mellitus, permanent neonatal diabetes diabetes mellitus, maturity-onset diabetes of the young type 10 and hyperproinsulinemia. There is a read-through gene, INS-IGF2, which overlaps with this gene at the 5' region and with the IGF2 gene at the 3' region. [provided by RefSeq, May 2020]
About eFluor 660
eFluor™ 660 (eF660) from Thermo Fisher Scientific has an excitation peak at 633 nm and an emission peak at 669 nm. It is useful in fluorescence microscopy and flow cytometry applications.
eFluor™ 660 (eF660) from Thermo Fisher Scientific has an excitation peak at 633 nm and an emission peak at 669 nm. It is useful in fluorescence microscopy and flow cytometry applications.
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